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Methadone is a synthetic opioid medication primarily used for the treatment of opioid dependence, including the management of opioid withdrawal symptoms and as part of medication-assisted treatment (MAT) programs. Methadone is classified as a full opioid agonist. It works by binding to the same receptors in the brain and spinal cord that are activated by other opioids, such as heroin or morphine. However, methadone's effects are longer-lasting, which helps to reduce withdrawal symptoms and cravings.