Tretinoin cream is a pharmaceutical drug in the dosage form of an ointment or cream formulation, tha

Retinoids reduce fine lines and wrinkles by increasing the production of collagen. They also stimulate the production of new blood vessels in the skin, which improves skin color. Additional benefits include fading age spots and softening rough patches of skin. However, it takes three to six months of regular use before improvements in wrinkles are apparent—and the best results take six to 12 months.